黄芪注射液对老年脑梗死恢复期胰岛素抵抗的影响

目的观察黄芪注射液对老年脑梗死恢复期胰岛素抵抗的影响。方法选择脑梗死恢复期患者 66例 ,按入院先后随机分为治疗组 3 3例 ,对照组 3 3例 ,两组均采用常规治疗 ,治疗组加用输液型黄芪注射液 ,疗程 2 0天 ,于治疗前后采取清晨空腹静脉血检测胰岛素 (Ins)、血糖 (FBS)、胆固醇 (CH)、甘油三酯 (TG)、空腹血清胰岛素 (FINS)以及血液流变学等 ,胰岛素抵抗用胰岛素敏感指数 (ISI)反映 ,并于治疗后进行相应的临床疗效评定。结果治疗组治疗后各项指标均有所降低 ,其中ISI明显降低 (P <0 0 1) ;同时CH、FBS、FINS以及血液流变学各异常指标均有改善 ,治疗前后及与对照组比较有显著性或高度显著性差异 (P <0 0 5或P <0 0 1) ;治疗组临床显效率亦明显优于对照组 (P <0 0 1)。结论黄芪注射液能明显降低老年脑梗死恢复期胰岛素抵抗、降低异常升高的血脂、血粘度 ,提高临床疗效等作用。

Effect of menbranous milkvetch root parenteral solution on insulin resistance of gerontism cerebral infarction in stage of recovery

ObjectiveTo study the effect of menbranous milkvetch root parenteral solution on insulin resistance of gerontism cerebral infarction in recovery stage.Methods66 patients with gerontism cerebral infarction were randomly divided into therapy group(33 cases) which received membranous milkvetch root parenteral solution and control group(33 cases).Both groups adopted routine treatment at the same time, the period was 20 days. Insulin(Ins), free blood sugar(FBS), total cholesterol(CH), triglyceride(TG), hemorheology and insulin resistance(indicating by index of insulin sensitive) of blood on empty stomach were evalutated before and after treatment. ResultsAfter treatment there was decrease in CH, FBS, FINS in therapy group than in control group( P <0.01 or P <0.05); the clinical effect in therapy group was better than in control group( P <0.01).ConclusionMembranous milkvetch root parenteral solution can significantly decrease insulin resistance, blood lipin, blood viscosity in recovery stage of gerontism cerebral infarction, and improve clinical efficiency.