|
|||||
|
|
| 人工神经网络模型在肺癌与胃癌或肠癌中的鉴别分析 | |
| 引用本文： | 周晓蕾,冯斐斐,张昭,秦利娟,吴拥军,聂广金,倪然,吴逸明,王静. 人工神经网络模型在肺癌与胃癌或肠癌中的鉴别分析[J]. 实用医学杂志, 2011, 27(18): 3312-3314. DOI: 10.3969/j.issn.1006-5725.2011.18.019 |
| 作者姓名： | 周晓蕾 冯斐斐 张昭 秦利娟 吴拥军 聂广金 倪然 吴逸明 王静 |
| 作者单位： | 1. 郑州大学第一附属医院呼吸内科,450052 2. 郑州大学公共卫生学院,450001 3. 郑州大学临床医学系,450001 |
| 基金项目： | 国家自然科学基金资助项目 |
| 摘 要： | 目的:应用人工神经网络技术,联合检测6种肿瘤标志对肺癌与胃癌或肠癌进行区分判别,建立肿瘤标志联合检测肺癌的辅助诊断模型。方法:采用放射免疫学、分光光度法、原子吸收分光光度法等方法,测定67例肺癌患者、47例胃癌患者和50例大肠癌患者血清中癌胚抗原(CEA)、胃泌素(gastrin)、神经元特异性烯醇化酶(NSE)、唾液酸(SA)、铜锌比值(Cu/Zn)、钙(Ca)等6项指标。建立基于人工神经网络的肺癌肿瘤标志智能诊断模型。结果:肺癌-胃癌的人工神经网络模型判别肺癌的灵敏度,特异度和准确度分别为100%、83.3%和93.5%;肺癌-肠癌模型判别肺癌的灵敏度、特异度和准确度分别为76.9%、100%和87.0%。结论:本研究成功建立基于人工神经网络技术的肿瘤标志物联合检测的人工智能诊断模型,对肺癌-胃癌、肺癌-肠癌中肺癌的鉴别诊断有助于提高肺癌的诊断率。 |
| 关 键 词： | 神经网络(计算机) 肺癌 肿瘤标志 胃癌 肠癌 |
The distinguishment of lung cancer with gastric cancer or colon cancer by artificial neural network |
|
| ZHOU Xiao-lei,FENG Fei-fei,ZHANG Zhao,QIN Li-juan,WU Yong-jun,NIE Guang-jin,NI Ran,WU Yi-ming,WANG Jing. The distinguishment of lung cancer with gastric cancer or colon cancer by artificial neural network[J]. The Journal of Practical Medicine, 2011, 27(18): 3312-3314. DOI: 10.3969/j.issn.1006-5725.2011.18.019 | |
| Authors: | ZHOU Xiao-lei FENG Fei-fei ZHANG Zhao QIN Li-juan WU Yong-jun NIE Guang-jin NI Ran WU Yi-ming WANG Jing |
| Affiliation: | ZHOU Xiao-lei*,FENG Fei-fei,ZHANG Zhao,QIN Li-juan,WU Yong-jun,NIE Guang-jin,NI Ran,WU Yi-ming,WANG Jing.*Department of Respiratory Disease,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China |
| Abstract: | Objective To distinguish lung cancer from gastric cancer or colon cancer by artificial neural network(ANN) combined with six serum tumor markers. Methods The levels of serum carcino-embryonic antigen(CEA), gastrin, neurone specific enolase(NSE), sialic acid(SA), Cu/Zn, Ca in 67 lung cancer patients, 47 gastric cancer patients and 50 colon cancer were detected by radioimmunology,spectrophotometry,or atomic absorption spectrophotometry,respectively.and artificial neural network were established with six serum... |
| Keywords: | Neural networks(computer) Lung cancer Tumor marker Gastric cancer Colon cancer |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |