| CT灌注成像辅助诊断胰腺癌 |
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| 引用本文： | 徐青,唐金华,徐化凤. CT灌注成像辅助诊断胰腺癌[J]. 医学影像学杂志, 2011, 21(9): 1362-1365 |
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| 作者姓名： | 徐青 唐金华 徐化凤 |
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| 作者单位： | 南京医科大学第一附属医院放射科 江苏南京210029 |
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| 摘 要： | 目的:CT灌注是一种新的功能成像方法,它能反映组织内的血液灌注的变化。本文旨在研究胰腺癌的CT灌注特征及探讨64层螺旋CT胰腺灌注成像在胰腺癌辅助诊断中的价值。方法:临床拟诊胰腺癌的患者49例,采用64层螺旋CT行胰腺灌注扫描,灌注扫描结束后进行常规胰腺双期扫描。对灌注参数:局部组织血流量(blood flow,BF)、血容量(blood volume,BV)、峰值(PE)、渗透性(permeability,P)和达峰时间(time to peak,TTP)进行统计分析。结果:12例因为技术原因或非胰腺癌病例而排除在外。剩下的37例包括13例正常胰腺和病理证实的胰腺癌24例。正常胰腺实质与胰腺癌周围的正常胰腺组织在BF(146.23 vs.119.37),BV(194.51 vs.173.67),PE(85.08 Vs.72.47),TTP(126.48 Vs.135.07),Permeability(84.86 Vs.69.11)上无统计学差异(P>0.05).胰腺癌组织的BF(55.10 Vs.146.23),BV(89.19 Vs.194.51),and PE(42.97 vs.85.08)明显低于瘤周的正常胰腺组织,差异有显著性(P<0.05)。但是两者的TTP(131.73 Vs.126.48)and Permeability(59.94 Vs.84.86)无明显差异(P>0.05)。结论:64层螺旋CT胰腺癌的灌注研究显示肿瘤的BF,BV,and PE明显减低.CT灌注扫描对胰腺癌的诊断有一定价值。
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| 关 键 词： | 胰腺癌 灌注 体层摄影术,X线计算机 |
CT perfusion aid in the diagnosis of pancreatic adenocarcinoma |
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| QING Xu,TANG Jin-hua,XU Hua-feng. CT perfusion aid in the diagnosis of pancreatic adenocarcinoma[J]. Journal of Medical Imaging, 2011, 21(9): 1362-1365 |
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| Authors: | QING Xu TANG Jin-hua XU Hua-feng |
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| Affiliation: | QING Xu,TANG Jin-hua,XU Hua-feng Department of Radiology,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,P.R.China |
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| Abstract: | Objective:CT perfusion is a new technique of function imaging,which can outline blood perfusion change in a tissue.We aimed to explore the perfusion characteristics of pancreatic adenocarcinoma and to determine whether 64-slice spiral CT with pancreas perfusion imaging could aid in diagnosing pancreatic adenocarcinoma.Methods:49 patients with suspected pancreatic adenocarcinoma underwent pancreas perfusion examination with 64-slice CT.After dynamic enhancement scanning,routine dual-phase scanning was perfor... |
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| Keywords: | Pancreatic adenocarcinoma Perfusion CT |
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