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| 60Co辐照对乌金丸中益母草碱的影响 | |
| 引用本文： | 李艳萍,曾煦欣,许锦涛,谭珍,颜金武,吴剑峰. 60Co辐照对乌金丸中益母草碱的影响[J]. 药学研究, 2017, 36(11): 643-645,651. DOI: 10.13506/j.cnki.jpr.2017.11.006 |
| 作者姓名： | 李艳萍 曾煦欣 许锦涛 谭珍 颜金武 吴剑峰 |
| 作者单位： | 1. 佛山科学技术学院口腔医学院<医药工程学院>,广东 佛山,528000;2. 佛山冯了性药业有限公司,广东 佛山,528000;3. 华南理工大学生物科学与工程学院,广东 广州,510006 |
| 基金项目： | 国家自然科学基金项目(21502056)，广东省普通高校青年创新人才项目(2014KQNCX182)，佛山科学技术学院创新强校项目 |
| 摘 要： | 目的 考察不同剂量60 Co辐照(0、2、6和10 kGy)对乌金丸有效成分益母草碱含量的影响.方法 采用梯度高效液相色谱(HPLC)法检测益母草碱的含量,应用SPSS软件对试验结果进行统计分析.结果 益母草碱在0、2、6和10 kGy的辐照处理后含量分别为0.138、0.135、0.139和0.137 mg·g-1.统计学分析发现,经不同剂量辐照灭菌后乌金丸中益母草碱的含量与无辐照相比无显著性差异(P>0.05).结论 60 Co辐照灭菌对乌金丸中益母草碱的含量无影响. |
| 关 键 词： | 乌金丸 60Co辐照灭菌 益母草碱 高效液相色谱 |
The effects of 60Co irradiation on leonurine in Wujin Pills |
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| LI Yanping,ZENG Xuxin,XU Jintao,TAN Zhen,YAN Jinwu and WU Jianfeng. The effects of 60Co irradiation on leonurine in Wujin Pills[J]. Journal of Pharmaceutical Research, 2017, 36(11): 643-645,651. DOI: 10.13506/j.cnki.jpr.2017.11.006 | |
| Authors: | LI Yanping ZENG Xuxin XU Jintao TAN Zhen YAN Jinwu WU Jianfeng |
| Affiliation: | 1.School of Stomatology and Medicine,Foshan University,Foshan 528000,China;2.Foshan Feng Liao Xing Pharmaceutical Company,Foshan 528000,China;3.School of Bioscience and Biotechnology, South China University of Technology,Guangzhou 510006 China,1.School of Stomatology and Medicine,Foshan University,Foshan 528000,China;2.Foshan Feng Liao Xing Pharmaceutical Company,Foshan 528000,China;3.School of Bioscience and Biotechnology, South China University of Technology,Guangzhou 510006 China,1.School of Stomatology and Medicine,Foshan University,Foshan 528000,China;2.Foshan Feng Liao Xing Pharmaceutical Company,Foshan 528000,China;3.School of Bioscience and Biotechnology, South China University of Technology,Guangzhou 510006 China,1.School of Stomatology and Medicine,Foshan University,Foshan 528000,China;2.Foshan Feng Liao Xing Pharmaceutical Company,Foshan 528000,China;3.School of Bioscience and Biotechnology, South China University of Technology,Guangzhou 510006 China,1.School of Stomatology and Medicine,Foshan University,Foshan 528000,China;2.Foshan Feng Liao Xing Pharmaceutical Company,Foshan 528000,China;3.School of Bioscience and Biotechnology, South China University of Technology,Guangzhou 510006 China and 1.School of Stomatology and Medicine,Foshan University,Foshan 528000,China;2.Foshan Feng Liao Xing Pharmaceutical Company,Foshan 528000,China;3.School of Bioscience and Biotechnology, South China University of Technology,Guangzhou 510006 China |
| Abstract: | Objective To analyze the influence of 60Co irradiation (0,2,6 and 10 KGy) on leonurine in Wujin Pills.Methods HPLC was used to detect the contents of leonurine in Wujin Pills,and the obtained results were further analyzed by SPSS.Results The average contents of leonurine in Wujin pill of 0,2,6and 10 KGy were 0.138, 0.135, 0.139 and 0.137 mg·g-1.By SPSS analysis,no statistical significance was found among above detected irradiation groups (P>0.05).Conclusion 60Co irradiation sterilization had no effect on leonurine content in Wujin Pills. |
| Keywords: | Wujin pills 60Co irradiation sterilization Leonurine HPLC |
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