息肉状脉络膜血管病变的临床表现分析

目的 探讨息肉状脉络膜血管病变(PCV)患者的流行病学特点及临床表现特征。 方法 回顾性分析2011年8月至2015年1月收治的PCV患者87例(107眼),分析其流行病学特点、眼底检查、荧光素钠眼底血管造影(FFA)及吲哚菁绿眼底血管造影(ICGA)检查资料。 结果 87例(107眼)PCV患者中,男性占57.5%(50例),单眼受累占77.0%(67例)。41~92岁,平均(66.4±9.4)岁。51.4%(55眼)见出血性视网膜色素上皮层脱离(PED),45.8%(49眼)见视网膜下橘红色隆起改变。77.6%(83眼)息肉状病灶位于黄斑区,息肉状病灶1~8个,平均(2.71±1.79)个,单灶性与多灶性息肉状病灶中最大者平均面积分别为(0.52±0.35)mm²和(0.49±0.37)mm²。 结论 PCV患者多见于男性,以单眼发病为主,临床表现为好发于黄斑区的出血性PED及视网膜下橘红色隆起改变,单灶性息状病的平均面积大于息肉状病灶中最大者的平均面积。

Clinical manifestations of polypoidal choroidal vasculopathy

Objective To investigate the demographic features and clinical manifestations of polypoidal choroidal vasculopathy (PCV).Methods We retrospectively reviewed 107 eyes in 87 consecutive outpatients with a diagnosis of PCV in the Department of Ophthalmology,Shandong Provincial Hospital from August 11,2011 to January 28,2015.All the patients underwent an epidemiological inquiry,routine eye examination,color fundus photography fluorescein angiography and indocyanine green angiography (ICGA).Results Among the 87 PCV patients,there was a male predominance with 50(57.5％) male patients.67(77.0％) patients were affected unilaterally.The average age was 66.4 ±9.4 years old (range,41-92).Based on fundus examination,the commonest clinical fundus feature was hemorrhagic pigment epithelial detachment (PED) (55 eyes,51.4％),which was followed by sub-retinal orange-red bulging lesions (49 eyes,45.8％).ICGA showed that polyps located in the macular area in 83 (77.6％) eyes.The average number of polypoidal lesions was 2.71 ± 1.79 (ranged from 1 to 8).The mean area of the solitary polyp and the largest one of multiple polyps was 0.52 ± 0.35 mm2,0.49 ± 0.37 mm2 respectively.Conclusion Among our patients with PCV,male,unilateral,macular location of polypoidal lesions with hemorrhagic PED and sub-retinal orange-red bulging lesion are the commonest clinical fundus manifestations.In ICGA,the mean area of PCV with solitary polyp was larger than the biggest one of PCV with multiple polyps.