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热熔挤出技术在药物制剂中的应用进展
引用本文:杨硕,王立,张文君,梁爽. 热熔挤出技术在药物制剂中的应用进展[J]. 药学研究, 2017, 36(11): 664-666. DOI: 10.13506/j.cnki.jpr.2017.11.012
作者姓名:杨硕  王立  张文君  梁爽
作者单位:哈尔滨商业大学药学院,黑龙江 哈尔滨,150076
摘    要:
本文综述了作为一种新颖的药物制剂技术——热熔挤出技术的优势、工艺与设备,以及热熔挤出技术在药物制剂中的诸多应用,并对该技术的应用前景进行展望.

关 键 词:热熔挤出  固体分散体  缓释制剂  靶向给药

Application progress of hot melt extrusion technology in pharmaceutical preparations
YANG Shuo,WANG Li,ZHANG Wenjun and LIANG Shuang. Application progress of hot melt extrusion technology in pharmaceutical preparations[J]. Journal of Pharmaceutical Research, 2017, 36(11): 664-666. DOI: 10.13506/j.cnki.jpr.2017.11.012
Authors:YANG Shuo  WANG Li  ZHANG Wenjun  LIANG Shuang
Affiliation:School of Pharmaceutical Sciences, Harbin University of Commerce, Harbin 150076, China,School of Pharmaceutical Sciences, Harbin University of Commerce, Harbin 150076, China,School of Pharmaceutical Sciences, Harbin University of Commerce, Harbin 150076, China and School of Pharmaceutical Sciences, Harbin University of Commerce, Harbin 150076, China
Abstract:
This paper reviews the advantages and processes and equipment of hot melt extrusion technology as a novel pharmaceutical preparation technology, as well as many applications of hot melt extrusion technology in pharmaceutical preparations, and prospects for the application of the technology.
Keywords:Hot melt extrusion   Solid dispersion   Sustained release preparations   Targeted drug delivery
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