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棉酚衍生物和类似物的抗生育作用
引用本文:王文华 于宗翰. 棉酚衍生物和类似物的抗生育作用[J]. 中国药理学报, 1990, 11(3): 268-271
作者姓名:王文华 于宗翰
摘    要:


关 键 词:棉酚 附睾 抗精子发生剂

Antifertility actions of gossypol derivatives and analogues
W H Wang,Z H Yu,M Cai,X M Xu,G P Wu. Antifertility actions of gossypol derivatives and analogues[J]. Acta Pharmacologica Sinica, 1990, 11(3): 268-271
Authors:W H Wang  Z H Yu  M Cai  X M Xu  G P Wu
Affiliation:Nanjing Institute of Materia Medica, China.
Abstract:
This paper reports the results of 32 gossypol derivatives and analogues. Among 12 compounds screened by oral administration to male rats, only dipotassium gossypolate (NC030) exhibited an antifertility activity similar to gossypol. Among 24 compounds screened by injecting into pouches of cauda epididymides of rats, 10 exhibited spermicidal activities.
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