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Pharmacokinetics of gentamicin in malnourrished infants |
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| Authors: | M. E. Bravo A. Arancibia S. Jarpa P. M. Carpentier A. N. Jahn |
| Affiliation: | (1) Instituto de Nutrición y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile;(2) Departmento de Ciencias Farmacológicas, Facultad del Ciencias Básicas y Farmacéuticas, Universidad de Chile, Santiago, Chile;(3) Cátedra de Pediatría, Hospital Calvo Mackenna, Facultad de Medicina, Universidad de Chile, Santiago, Chile |
| Abstract: | Summary The pharmacokinetics of gentamicin was investigated in normal and malnourished infants aged 4–10 months. Neither mean  elimination nor distribution half life show any difference, but the volume of distribution was higher in malnourished babies, probably due to their larger total body water. |
| Keywords: | gentamicin malnutrition pharmacokinetics infant |
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