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Patent foramen ovale diagnosis: The importance of provocative maneuvers
Authors:Silvia Mongodi MD  PhD  Gabriele Via MD  Mariachiara Riccardi MD  Guido Tavazzi MD  Andrea Maria D'Armini MD  Marco Maurelli MD  Antonio Braschi MD  Francesco Mojoli MD
Affiliation:1. Anesthesia and Intensive Care, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy;2. Cardiothoracic Surgery, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy
Abstract:Patent foramen ovale (PFO) is a frequent congenital anomaly, but massive right‐to‐left shunt (RTLS) is normally prevented by higher pressures in left heart chambers. However, mechanical ventilation with positive end‐expiratory pressure (PEEP) can significantly increase right atrial pressure, accentuating the RTLS, mainly after major cardiothoracic surgery. We report a patient admitted to the intensive care unit after cardiac surgery. Pre‐ and intraoperative transesophageal echocardiography only described an aneurysmal interatrial septum with no shunt. However, high‐PEEP ventilation induced a paradoxical response with life‐threatening hypoxemia, triggering further echocardiographic evaluation, revealing massive RTLS across a stretch PFO. Provocative maneuvers (Valsalva/PEEP) significantly increase echocardiographic sensitivity, unmasking silent PFO. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 45 :58–61, 2017
Keywords:patent foramen ovale  provocative maneuvers  right‐to‐left shunt  echocardiography  paradoxical response to positive end‐expiratory pressure
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