| 脑胶质瘤EGFR、p53蛋白和PCNA的表达与生物学行为 |
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| 引用本文： | 叶廷军,陈詠莲,刘会敏.脑胶质瘤EGFR、p53蛋白和PCNA的表达与生物学行为[J].肿瘤学杂志,1996(2). |
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| 作者姓名： | 叶廷军 陈詠莲 刘会敏 |
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| 作者单位： | 第二军医大学长征医院!上海，200003，第二军医大学长征医院!上海，200003，第二军医大学长征医院!上海，200003 |
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| 摘 要： | 本文联合检测了58例脑胶质瘤EGFR、p53蛋白和PCNA的表达，结果表明，三者的表达率均随胶质瘤的级别升高而增高增强．高级别组与低级别组相比较，有显著差异（P＜0．01），复发组与未复发组相比较．有显著差异（P＜0．01）．提示肿瘤的生物学行为与表达的高低有关，肿瘤的生物学行为越差，表达率就越高．染色强，预后越差。
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| 关 键 词： | 胶质瘤 表皮生长因子 p53蛋白 增殖细胞核抗原 |
Expression of EGFR, p53 protein and PCNA and the biological behavior in the gliomas |
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| Ye Tingjun, Chen Yonglian, Liu Huimin.Expression of EGFR, p53 protein and PCNA and the biological behavior in the gliomas[J].Journal of Oncology,1996(2). |
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| Authors: | Ye Tingjun Chen Yonglian Liu Huimin |
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| Abstract: | The expression of EGFR, p53 protein and PCNA and biological behavior in the glioma was studied. The result showsthat the increase of EGFR, p53 protein and PCNA expresion associated with increased grade of gliomas. The positive rate of expressionwas higher in the high grade group than that in low one. The difference was statistically significant (P<0.01). There was significantdifference between recurrsent group and disease free group. The expression of EGFR,p53 protein and PCNA was closely related to thebiological behavior of gliomas. |
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| Keywords: | Gliomas EGFR p53 protein PCNA |
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