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齐拉西酮与利培酮治疗精神分裂症对照研究
引用本文:王刚平,颉瑞,裴根祥,张永录. 齐拉西酮与利培酮治疗精神分裂症对照研究[J]. 临床精神医学杂志, 2008, 18(1): 55-56
作者姓名:王刚平  颉瑞  裴根祥  张永录
作者单位:甘肃天水市精神病医院,741000;甘肃天水市精神病医院,741000;甘肃天水市精神病医院,741000;甘肃天水市精神病医院,741000
摘    要:
目的:探讨齐拉西酮对首发精神分裂症患者的临床疗效及安全性。方法:60例精神分裂症患者随机分为两组,分别给予齐拉西酮与利培酮治疗8周,用阳性与阴性症状量表(PANSS)和治疗中出现的症状量表(TESS)评定疗效和不良反应。结果:齐拉西酮组与利培酮组疗效相仿(P〉0.05),齐拉西酮组不良反应显著少于利培酮组(P〈0.05).结论:齐拉西酮是一种安全有效的抗精神病药。

关 键 词:精神分裂症  齐拉西酮  利培酮
文章编号:1005-3220(2008)01-0055-02
收稿时间:2007-03-12
修稿时间:2007-03-22

Comparative study between ziprasidone and risprasidone in treatment of schizophrenia
WANG Gang-ping,XIE Rui,PEI Gen-xiang,ZHANG Yong-lu. Comparative study between ziprasidone and risprasidone in treatment of schizophrenia[J]. Journal of Clinical Psychological Medicine, 2008, 18(1): 55-56
Authors:WANG Gang-ping  XIE Rui  PEI Gen-xiang  ZHANG Yong-lu
Affiliation:WANG Xiao-quan, ZHOU Hai-xiao, ZHANG Yong-lu, LI Gang, XIE Pei-liang( Tianshui Mental Hospital, Tianshui 741000, China)
Abstract:
Objective:To study the clinical efficacy and side effects of ziprasidone in the treatment of first-onset schizophrenia.Method:Sixty schizophrenic inpatients were divided into ziprasidone group or risperidone group randomly for 8 weeks.Positive and negative symptoms scale(PANSS)and treatment emergent symptom scale(TESS)were used to evaluate the efficacy and side effects respectively.Results:There were no significant differences in efficacy between two groups(P>0.05).Ziprasidone had less side effects than risperidone significantly(P<0.05).Conclusion:Ziprasidone is a safe and effective antipsychotic drug.
Keywords:schizophrenia  ziprasidone  risperidone
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