Clinical Profile of HLA B-27-Associated Uveitis Patients in a Tertiary Care Eye Hospital in Eastern India |
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| Authors: | Anindya K. Majumdar Amitabh Kumar Rupak Roy Parthopratim Dutta Majumder |
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| Affiliation: | 1. Department of Uvea, Aditya Birla Sankara Nethralaya, Kolkata, Indiaanindya.einstein@gmail.com;3. Department of Uvea, Aditya Birla Sankara Nethralaya, Kolkata, India;4. Vitreo Retina Services, Aditya Birla Sankara Nethralaya, Kolkata, India;5. Department of Uvea, Sankara Nethralaya, Chennai, India |
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| Abstract: | ![]()
Purpose: To analyse clinical profile of the patients with HLA B 27- associated uveitis in a tertiary care eye hospital in Eastern India Method: Retrospective analysis of 61 eyes of 43 patients with HLA B27- associated uveitis between 2015 and 2016. Result: We observed a male predominance (67%), and more unilateral involvement (58%) in our patients. The mean age of presentation was 44.7 ±11.7 years. Significant vitritis and macular edema were noted in 14 and 7 eyes respectively. In addition to topical therapy, oral steroid was required in 49% patients and 58% patients were treated with methotrexate. Five patients (12%) required biologicals. There was improvement in BCVA at final follow-up (p<0.001). Conclusion: Compared to the existing literature, the current study observed relatively high age of presentation and frequent posterior segment involvement with less systemic association. |
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| Keywords: | Anterior uveitis HLA B 27 macular edema vitritis retinal vasculitis |
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