经鼻双水平通气对新生儿呼吸窘迫综合征的疗效分析

目的探讨经鼻双水平通气(Bi PAP)对新生儿呼吸窘迫综合征(NRDS)的治疗效果。方法选择88例NRDS患儿,随机分为对照组组和观察组,每组44例;对照组给予CPAP治疗,而观察组则给予Bi PAP治疗;比较两组的治疗前后的血气分析、临床效果及预后等指标。结果观察组治疗后的Pa O2水平升高程度大于对照组(P<0. 01),而观察组治疗后的Pa CO2水平降低程度也大于对照组(P<0. 01);观察组的通气时间、氧疗时间、住院时间及住院费用均低于对照组(P<0. 05);观察组的脱机成功率为88. 64%,高于对照组的68. 18%(P <0. 05);而观察组的并发症发生率为9. 09%,低于对照组的27. 27%(P<0. 05)。结论 NRDS患儿通过Bi PAP治疗后,可有效增加肺泡气体交换,改善血气分析指标,提高临床治疗效果,降低并发症,改善患儿预后。

Study on treatment effect of neonatal respiratory distress through the treatment of biphasic positive airway pressure

Objective To explore the treatment effect of nasal biphasic positive airway pressure( Bi PAP) treating patients of neonatal respiratory distress syndrome( NRDS). Methods 88 cases of NRDS were randomly divided into control group and observation group,44 cases each group. The control group was adopted CAPA treatment,and the observation group was given Bi PAP treatment. The indexes of blood gas analysis,clinical effect and prognosis were compared between the two groups before and after treatment. Results The elevation level of Pa O2 in the observation group after treatment was larger than the control group( P<0. 01),but the descending level of Pa CO2 in the observation group was also lager than the control group( P<0. 01). The levels of ventilation time,oxygen therapy time,length of stay and hospitalization expenses in the observation group were all lower than the control group( P<0. 05). The success rate of offline in the observation group was 88. 64%,higher than the control group( 68. 18%,P < 0. 05). But the rate of complications in the observation group was9. 09%,lower than the control group( 27. 27%,P<0. 05). Conclusion NRDS patients after the treatment of Bi PAP,it could effectively increase of alveolar gas exchange,improve blood gas analysis indexes,raise clinical treatment effect,cut down complications,and improve prognosis of patients.