可吸收DL－聚乳酸夹板行颌面部骨折内固定的实验研究

对ＤＬ－聚乳酸（ＰＤＬＬＡ）夹板在８只狗的下颌骨、颧弓骨折内固定的疗效，进行了实验研究。采用大体、组织学、四环素荧光活体骨标记、Ｘ线摄片，观察骨折４，８，１２，２８周时的内固定效果；ＰＤＬＬＡ板的组织相容性及其在体内的降解，并与微型钢折内固定比较。结果表明：１．超高分子ＰＤＬＬＡ板具有良好的力学性能，在下颌体、颧弓骨折内固定中可获得良好固位，达到与微型钢板相同的内固定效果。２．ＰＤＬＬＡ板具有良好的组织相容性，不引起周围组织的炎症和异物反应。３．ＰＤＬＬＡ板植入后脆性逐渐增加，术后３月仍呈原有外形，但重量下降，术后７月已降解为碎片和小颗粒，重量丧失７０％以上，但何时完全吸收有待更远期观察。

Resorbable Plates of Poly (DL-Lactide) for Internal Fixation of Maxillofacial Fracture: An Experimental Study in Dogs

dogs were treated with resorbable PDLLA plates for internal fixation of zygomatic arch fractures and mandibular fractures. Histology, tetracycline bone labelling in vivo,x-ray photograph were taken, and compared the bone healing with the mini metal plates. The results showed that: 1. The PDLLA plates had the same effect of internal fixation of mini metal plates.2. There was no tissue reaction to PDLLA plates.3 .PDLLA plates had degraded into irregular granule after 7 months. It is unknown how long it had disappeared.