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早产儿N端脑钠肽前体水平的临床意义研究进展
引用本文:严芳,张智,李楠,李泽泳. 早产儿N端脑钠肽前体水平的临床意义研究进展[J]. 医疗保健器具, 2011, 18(10): 1653-1655. DOI: 10.3969/j.issn.1674-4659.2011.10.1653
作者姓名:严芳  张智  李楠  李泽泳
作者单位:广东省第二人民医院生物实验中心,广东,广州,510317
摘    要:
随着生物技术的发展,脑钠肽在新生儿中的作用逐渐突显。目前,B型脑钠肽(BNP)和N末端脑钠肽前体(NTpBNP)应用于成人的心肌功能和容量负荷评估,且二者在心脏外科手术的预后评估中的作用已得到证实。而NTpBNP有可能成为新生儿动脉导管未闭(PDA)症的筛查工具,以及心肌性能的标志。另外,NTpBNP有可能预测早产儿和足月儿新天性膈疝(CDH)的预后情况。本文综述了NTpBNP检测对早产儿的临床意义。

关 键 词:B型脑钠肽  N末端脑钠肽前体  早产儿

The Use of N-Terminal-Pro-BNP in Preterm Infants
YAN Fang,ZHANG Zhi,LI Nan,LI Zeyong. The Use of N-Terminal-Pro-BNP in Preterm Infants[J]. Medicine Healthcare Apparatus, 2011, 18(10): 1653-1655. DOI: 10.3969/j.issn.1674-4659.2011.10.1653
Authors:YAN Fang  ZHANG Zhi  LI Nan  LI Zeyong
Affiliation:YAN Fang,ZHANG Zhi,LI Nan,LI Zeyong (Biology Experiment Center,Guangdong No.2 Provincial People's Hospital,Guangzhou 510317,China)
Abstract:
With the development of biological technology, the use of natriuretic peptides in the neonatal population is emerging. B-type Natriuretic Peptide (BNP) and N-terminal-Pro-BNP (NTpBNP) are used in the adult population to assess myocardial function and volume loading. Their role in prognosis following cardiac surgery has also been identified. In preterm infants NTpBNP is becoming increasingly recognised as a potential screening tool for patent ductus arteriosus (PDA), and a marker for myocardial performance. ...
Keywords:B-type Natriuretic Peptide  N-terminal-Pro-BNP  Preterm infant  
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