前列腺外腺增生性低回声结节的组织形态学定量研究

目的:探讨前列腺外腺增生性低回声结节的组织形态学特点。　方法:应用苏木精 伊红染色和免疫组化染 色结合计算机辅助图像分析方法,对22例病理证实为良性前列腺增生的外腺低回声结节穿刺标本进行组织成分定 量分析。　结果:前列腺外腺增生性低回声结节中间质、上皮、腺腔和间质中平滑肌成分所占整个前列腺组织的面 积百分比分别为(72.52±13.14)%、(20.57±9.01)%、(6.85±4.51)%和(24.14±6.31)%。　结论:与前列腺内 腺一样,前列腺外腺也可出现增生性低回声结节,但两者的成分构成百分比有所不同。

Quantitative Morphometry of Hyperplastic Hypoechoic Nodules in the Prostatic Outer Gland

OBJECTIVE: To explore the morphotic characteristics of hypoechoic nodules in the outer gland of the prostate with benign METHODS: Twenty-two hyperplastic hypoechoic nodules in the prostatic outer gland were biopsied guided by prostatic hyperplasia. transrectal ultrasound. The hematoxylin-eosin (HE) staining and immunohistochemistry combined with computer assisted quantitative image analyses were adopted to examine the mean percentages of the area densities of stroma, epithelium, glandular lumen and smooth muscle cells. RESULTS: The area densities of stroma, epithelium, glandular lumen and smooth muscle cells were (72.52 +/- 13.14)%, (20.57 +/- 9.01)%, (6.85 +/- 4.51)% and (24.14 +/- 6.31)%, respectively. CONCLUSION: Hyperplastic hypoechoic nodules may develop in the outer gland as well as in the inner gland of the prostate, but the mean percentages of the components are different between the two kinds of nodules.