| 新型含药聚乙烯醇水凝胶创面敷膜的细胞毒性研究 |
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| 引用本文： | 李亦文 薛淼. 新型含药聚乙烯醇水凝胶创面敷膜的细胞毒性研究[J]. 口腔材料器械杂志, 1996, 5(4): 167-168 |
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| 作者姓名： | 李亦文 薛淼 |
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| 作者单位： | 上海生物材料研究测试中心，上海生物材料研究测试中心，上海生物材料研究测试中心，上海生物材料研究测试中心，上海生物材料研究测试中心，上海大学射线应用研究所，上海大学射线应用研究所 200023，200023，200023，200023，200023 |
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| 摘 要： | 本研究采用改进的细胞相对增殖度法和细胞形态学方法研究了新型含药聚乙烯醇创面敷膜的组织相容性。含药ＰＶＡ敷膜第２，４，７天的细胞相对增殖度分别为８６％，９５％和１０２％，基本无细胞毒性。通过分别于第２４。４８，７２小时的形态学观察可见，与敷膜接触的细胞生长状态良好。因此此敷膜具有良好的组织相容性
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| 关 键 词： | 聚乙烯醇 创面敷膜 细胞毒性 牙科材料 |
Histocompatibility of a PVA Wound Dressing with Drug Delivery System |
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| Li Yiwen,Xue Miao,Ning Li,et al Shanghai Biomaterial Research and Test Center,Shanghai Second Medical University. Histocompatibility of a PVA Wound Dressing with Drug Delivery System[J]. Chinese Journal of Dental Materials and Devices, 1996, 5(4): 167-168 |
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| Authors: | Li Yiwen Xue Miao Ning Li et al Shanghai Biomaterial Research Test Center Shanghai Second Medical University |
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| Abstract: | Histocompatibility of the wound dresing with drug delivery system was studied with the advanced Cell Relative Growth Rate Test and the Cell Morphology Test. The cell strain was L -929 fibroblast and the culture medium was Eagle's MEM with 10% calf serum and 1% glutamine. On the day 2, day 4 and day7, the cell relative growth rate (RGR) of the dressing were 86%, 95%,102% respectively. The grade of the cytotoxicity of the intelligent film was 0, so the dressing had no cytotoxicity. On day 1, day 2 and day 3, the cells which directly contacted with the wound dressing samples were observed through the Olympus IM microscope in the Cell Morphology Test and the morphology of the cells was excellent. The results stated the good histocompatibility of the new PVA wound dressing. |
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| Keywords: | Histocompatibility PVA Wound Dressing |
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