Yakammaoto inhibited human coxsackievirus B4 (CVB4)-induced airway and renal tubular injuries by preventing viral attachment,internalization, and replication |
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| Authors: | Ming Hong Yen Jia Jung Lee Chia Feng Yeh Kuo Chih Wang Ya Wen Chiang Lien Chai Chiang Jung San Chang |
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| Affiliation: | 1. School of Pharmacy and Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Taiwan;2. Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan;3. Department of Renal Care, College of Medicine, Kaohsiung Medical University, Taiwan;4. Department of Microbiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Taiwan;5. Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan |
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| Abstract: | ![]()
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| Keywords: | ATCC, the American Type Culture Collection CC50, 50% cytotoxic concentration CVB4, human coxsackievirus B4 DMSO, dimethylsulfoxide ELISA, enzyme-linked immunosorbent assay FCS, fetal calf serum HEp-2, human larynx epidermoid carcinoma cell HK-2, human kidney 2 cell IC50, minimal concentration required to inhibit 50% plaque formation IFN, interferon DMEM, Dulbecco's Modified Eagle medium PBS, phosphate-buffered saline pfu, plaque forming unit SI, selectivity index TCM, traditional Chinese medicine TMB, 3,3',5,5'-tetramethylbenzidine Yakammaoto, Ye-Gan-Ma-Huang-Tang (Taiwan) She-Gan-Ma-Huang-Tang, Sheganmahuang decoction (Chinese) |
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