新兵人群Y群流行性脑脊髓膜炎抗体水平回顾性血清流行病学调查

目的了解入伍新兵人群中Y群流脑IgG抗体的流行分布情况,为今后预防提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对北京军区近4年来自7个省市的360名入伍新兵血清进行了Y群流脑IgG抗体检测,统计分析其阳性率。结果发现各年间入伍新兵血清Y群流脑IgG抗体历年间无显著变化,为28.57%～60.78%,平均43.61%;抗体含量,为0.000～98.622μg/ml,平均4.590μg/ml;地区间差别显著,内蒙古(60.78%)、陕西省(55.00%)和湖北省(48.33%)较高,山东省(28.57%)和北京市(33.33%)较低;入伍前工作与否,抗体阳性检出率无显著性差别;其差别的主要原因可能与各地区隐性感染和时间长短有关。结论入伍新兵人群中Y群流脑IgG抗体阳性率为28.57%～60.78%,抗体平均含量,为4.590μg/ml,并有显著性地区差异;所以,在新兵入伍期间,采取预防接种、健康教育等有效预防措施。

Retrospective seroepidemiology study of serogroup Y epidemic cerebrospinal meningitis antibody level in recruits

Objective This study was conducted to investigate the distribution of serogroup Y epidemic cerebrospinal meningitis antibody IgG in recruits,provide scientific evidence for further prevention and control of the disease.Methods A seroepidemiological study was conducted by using Enzyme-Linked Immuno Sorbent Assay (ELISA).Serum samples of 360 recruits (from 7 provinces during the past four years) were tested to detect sero-group Y epidemic cerebrospinal meningitis antibody IgG,and the overall positive rate was...