我院2011-2013年中药注射剂使用情况分析

目的:为中药注射剂的临床合理应用提供参考。方法:从医院信息系统中收集我院2011-2013年中药注射剂的品种、用药金额、用药频度(DDDs)、日均费用(DDC)、排序比(DUI)及不良反应(ADR)等数据,并采用Excel 2003软件进行统计分析及排序。结果:我院2011-2013年中药注射剂的用药金额、DDDs、DDC均呈逐年上升趋势,但品种数较为稳定,均为23种。其中,心脑血管类中药注射剂品种最多,其用药金额占所有中药注射剂的一半以上,且DDDs排序最高的前10名药物中有7种为心脑血管用药;呼吸系统类的用药金额增长最为显著,2013年较2011年增长了98.1%,主要为喜炎平注射液的用量增长所致。2011-2013年发生的中药注射剂ADR类别大部分为一般ADR,多表现为过敏反应和胃肠道反应等,干预后其发生率2013年较2012年下降了50%。结论:我院中药注射剂的使用基本合理,个别品种存在使用不规范的情况。今后应继续加强对中药注射剂临床应用的监管,以保证用药安全、有效。

Analysis of the Utilization of TCM Injection in Our Hospital during 2011-2013

OBJECTIVE ： To provide reference for rational use of TCM injection. METHODS ： By collecting TCM injection in- formation from HIS, the utilization of TCM injection in our hospital during 2011--2013 was analyzed statistically with Excel 2003 software in respects of type, consumption sum, DDDs, DDC, DUI and ADR, etc. RESULTS. The consumption sum, DDDs and DDC of TCM injection in our hospital showed an upward trend from 2011 to 2013. The number of TCM injection type kept stable at 23 types; most of them were cardio-cerebrovascular TCM injection and their consumption sum occupied more than half of all TCM injection; among top 10 TCM injection in the list of DDDs, 7 kinds were cardio-cerebrovascular injection. The growth in con- sumption sum of respiratory system agents was the most significant, and that increased by 98.1% in 2013, compared with 2011, which was induced by the increase of Xiyanping injection. General ADR took up the great proportion, and manifested as allergic re- action and gastrointestinal reaction, etc. After intervention, the incidence of TCM injection-induced ADR decreased by 50% in 2013, compared with 2012. CONCLUSIONS： The application of TCM injections in our hospital is rational basically, but non-stan- dard use is found in individual species. The supervision of the clinical application of TCM injections should be strengthened to guar- antee the safe and effective use of drugs in the clinic.