生长抑素和凝血酶治疗小儿上消化道出血的疗效观察

目的探讨小儿上消化道出血的临床治疗方法。方法选取2004年5月至2009年8月中山大学附属第一医院儿科诊治的80例上消化道出血患儿,随机分为治疗组及对照组各40例,治疗组在常规治疗的基础上予生长抑素联合凝血酶治疗,对照组予常规治疗,比较两组疗效。结果治疗组显效30例,总有效例数38例,总有效率为95%,而对照组显效18例,总有效例数30例,总有效率为75%,治疗组疗效明显优于对照组,差异有统计学意义(P<0.05)。结论生长抑素和凝血酶治疗小儿上消化道出血疗效显著。

The Curative Effect of Somatostatin and Thrombin in Treatment of Upper Gastrointestinal Hemorrhage in Children

Objective To explore the treatment of upper gastrointestinal hemorrhage in children.Methods To select 80 children of upper gastrointestinal hemorrhage that treated in First Affiliated Hospital of Sun Yat-Sen University from May 2004 to August 2009.They were grouped randomly into treatment group（40 cases） and control group（40 cases）.Patients in treatment group were given somatostatin and thrombin on the base of conventional therapy.Patients in control group were treated with conventional therapy.The effect of these two groups was under observation.Results There were 30 cases in treatment group showed obvious effect,and the total effective number is 38.The effectiveness ratio is 95%.There were 18 cases in control group showed obvious effect,and the total effective number is 30.The effectiveness ratio is 75%.The variance was of statistical significance（P0.05）.Conclusions It was of evident effect to treat upper gastrointestinal hemorrhage in children with somatostatin and thrombin.