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Assessment of Serum microRNA Biomarkers to Predict Reclassification of Prostate Cancer in Patients on Active Surveillance
Authors:Richard S.C. Liu  Ekaterina Olkhov-Mitsel  Renu Jeyapala  Fang Zhao  Kristina Commisso  Laurence Klotz  Andrew Loblaw  Stanley K. Liu  Danny Vesprini  Neil E. Fleshner  Bharati Bapat
Affiliation:1. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada;2. Lunenfeld Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada;3. Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada;4. Division of Urology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
Abstract:
Keywords:prostatic neoplasms  microRNAs  biomarkers  tumor  watchful waiting  predictive value of tests  3-miR  miRNA-223, miRNA-24 and miRNA-375  AS  active surveillance  DRE  digital rectal examination  GS  Gleason score  miRNA  microRNA  MRI  magnetic resonance imaging  NPV  negative predictive value  PCa  prostate cancer  PHI  Prostate Health Index  PSA  prostate specific antigen  PSA-DT  PSA doubling time  UHN  University Health Network
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