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大鼠孤束核内5-羟色胺能轴突终末的突触联系
引用本文:陈良为,施际武,饶志仁. 大鼠孤束核内5-羟色胺能轴突终末的突触联系[J]. 解剖学报, 1994, 0(3)
作者姓名:陈良为  施际武  饶志仁
作者单位:第四军医大学解剖学教研室
摘    要:
用顺行演变与免疫组织化学结合的双标技术,电镜下观察大鼠孤束核内5-羟色胺样免疫反应(5-HT-LI)轴突终末的突触联系,特别是与迷走神经初级传入(溃变)终末的关系。发现:1.5-HT-LI轴突终末和迷走神经初级传入终末终止于同一个树突形成轴-树突触;2.5-HT-LI轴突终末与树突形成轴-树突触;3.5-HT-LI轴突终末与迷走神经初级传入终末或非标记的轴突终未形成轴一轴相贴(axo-axonic-contact)。以上结果提示,孤束核内的5-HT能神经成分可能通过突触后、突触前机制调控经迷走神经传入的信息。

关 键 词:孤束核,5-羟色胺,迷走神经初级传入,顺行溃变,电镜,免疫组织化学,大鼠

SYNAPTIC CONNECTIONS OF THE SEROTONINERGIC AXON TERMINALS IN NUCLEUS TRACTUS SOLITARIUS OF THE RAT
Chen Liangwei,Rao Zhiren,Shi Jiwu. SYNAPTIC CONNECTIONS OF THE SEROTONINERGIC AXON TERMINALS IN NUCLEUS TRACTUS SOLITARIUS OF THE RAT[J]. Acta Anatomica Sinica, 1994, 0(3)
Authors:Chen Liangwei  Rao Zhiren  Shi Jiwu
Abstract:
The synaptic connections of the serotonin-like immunoreactive(5-HT-LI)axon terminals,especially their relationship with vagal afferents in the nucleus tractus solitarius(NTS)of the rat were examined under electron microscope by double labelling technique combined with anterograde degeneraton and immunohistochemistry.We found:1.5-HT-LI axon terminals and degenerated axon terminals of the vagal afferents converged on same dendrites;2.5-HT-LI axon terminals formed axo-dendritic synapses with dendrites;3.5-HT-LI axons formed axo-axonic contacts with degenerated vagal afferent axon terminals or with normal axon terminals.These results suggested that in the NTS serotoninerggic neuroelements may modulate the visceral informations via the vagal afferents by postsynaptic mechanism and also possibly by pre-synaptic mechanism.
Keywords:Nucleus tractus solitarius  Serotonin  Vagal afferent  Anterograde degene ration  Electron microscope  Immunohistochemistry  Rat  
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