中国6223例急性胰腺炎病因及病死率分析

目的 调查我国急性胰腺炎（AP）的主要病因及病死率，为临床诊疗工作提供参考依据。方法 收集我国12所医院收治的AP患者，采用统一的软件记录患者的临床流行病学、实验室检查、影像学检查及相关的临床治疗经过，然后对所有患者的病因及病死率进行分析总结。结果 所收集的6223例患者中，重症急性胰腺炎（sAP）1743例，轻症急性胰腺炎（MAP）4480例。胆源性胰腺炎3385例，占54．4％；特发性胰腺炎1228例，占19．7％；高脂血症性胰腺炎782例，占12．6％；酒精性胰腺炎仅496例，占8．O％。284例患者病死，总病死率4．6％；SAP病死率15．6％，MAP为O．3％。结论 胆道疾病是我国AP的主要病因，SAP中以特发性胰腺炎的病死率最高，AP患者的病死率与高龄有关。

Etiology and mortality of acute pancreatitis in China: analysis of 6 223 clinical cases

Objective To investigate the etiology and associated mortality of acute pancreatitis (AP) in China so as to provide references for the clinical diagnosis and treatment of AP. Methods Medical records were reviewed and analyzed of 6 223 AP patients who were admitted in 12 hospitals in China from September 1995 to September 2005 in terms of etiology and mortality. Results Of the 6 223 patients, 1 743 patients had severe acute pancreatitis, 4 480 patients had mild pancreatitis. 3 385 patients (54.4%) had biliogenic pancreatitis, 1 228 patients (19.7%) had idiopathic pancreatitis, 782 patients (12.6%) had hyperlipemic pancreatitis, and 496 patients (8.0%) had alcoholic pancreatitis. 284 patients was died and the overall mortality of AP was 4.6%. The mortality rate of severe acute pancreatits was15.6%, while that of mild acute pancreatits was 0.3%. Conclusions The results of the present investigation showed that biliary tract disease is the main etiologic cause of AP in China; severe idiopathic pancreatitis has the highest mortality rate, and that there is an evident relationship between the mortality and old age.