Association between reproductive variables and metabolic syndrome in chinese community elderly women |
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| Institution: | 1. Institute of Geriatrics, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China;2. Beijing Key Laboratory of Aging and Geriatrics, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China;3. State Key Laboratory of Kidney Disease, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China;4. Department of Chinese Traditional Medicine and Acupuncture, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China;5. Department of Geriatric Cardiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China;1. Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Peking University Research Center on Aging, Beijing, China;2. College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA;1. Department of Family Medicine, Siaal Research Center for Family Medicine and Primary Care, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 84105, Israel;2. Yasski Clinic, Comprehensive Geriatric Assessment Unit, Clalit Health Services, 24 King David St., Beer-Sheva 84541, Israel;3. Unit for Community Geriatrics, Division of Health in the Community, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva, Israel;4. Clalit Health Services, Southern District, KENYON HANEGEV Towers, 3rd floor, Beer-Sheva, Israel;1. Department of Anatomy, Marmara University School of Medicine, Istanbul, Turkey;2. Department of Anatomy, Otago University, New Zealand;3. Department of Pharmacology and Clinical Pharmacology, School of Medicine, Marmara University, Istanbul - Turkey;4. Department of Anatomy, Koç University School of Medicine, Istanbul, Turkey;1. Department of Orthopaedics, Foshan Hospital of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China;2. Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, China;3. Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China;1. Division of Metabolism, Endocrinology and Diabetes, University of Michigan Hospital and Health Systems, Domino’s Farms, Lobby G, Suite 1500, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106, USA;2. Division of Geriatric and Palliative Medicine, University of Michigan Geriatrics Center, 300 North Ingalls, Room 901, Ann Arbor, MI 48109-2007, USA;1. Department of Anatomy, School of Medicine, Koç University, Sarıyer, Istanbul, Turkey;2. Department of Anatomy, School of Medicine, Marmara University, Istanbul, Turkey;3. Department of Histology-Embryology, School of Medicine, Koç University, Sarıyer, Istanbul, Turkey;4. Department of Pharmacology and Clinic Pharmacology, School of Medicine, Marmara University, Istanbul, Turkey |
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| Abstract: | ObjectiveThis study aimed to evaluate the association between reproductive variables and metabolic syndrome (MetS) among Chinese community elderly women.MethodsWe conducted a cross-sectional study in a Beijing urban district. A two-stage stratified clustering sampling method was used and 1251 elderly women were included.ResultsThe prevalence of MetS was 65.1% in this population. Women with MetS had younger menarche age, a greater number of years after menopause, higher gravidity and parity. The prevalence of MetS showed an increasing trend for tertiles of years after menopause (p = 0.002) and number of children (p < 0.001), while decreasing trend for menarche age (p = 0.021). Logistic regression showed ORs of age at menarche, years after menopause and number of children for MetS were 0.94, 1.40, and 1.36 for second and 0.63, 1.58, and 1.75 for last tertiles.ConclusionThere is strong association between reproductive variables and higher risk of MetS. Simple information on timing of menarche and menopause could help identify women who may have higher risk of getting MetS and take early action to prevent related chronic diseases. |
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| Keywords: | Reproductive factor Menarche Menopause Metabolic syndrome Elderly |
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