Noninvasive Tape-Stripping with High-Resolution RNA Profiling Effectively Captures a Preinflammatory State in Nonlesional Psoriatic Skin |
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| Affiliation: | 1. Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA;2. Department of Computational Medicine & Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA;3. Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA;4. Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA;5. Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, China;6. Division of Pediatric Rheumatology, Department of Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA;7. AbbVie Inc., Cambridge, Massachusetts, USA;8. Department of Dermatology, School of Medicine, UC-Davis Medical Center, Sacramento, California, USA;9. Divison of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA;10. Division of Rheumatology, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA;11. AbbVie Inc., North Chicago, Illinois, USA;1. Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany;2. Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan;3. Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA;4. Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden;5. Genovis AB, Lund, Sweden;6. Department of Dermatology, University of Lübeck, Lübeck, Germany;1. Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden;1. Institute of Molecular Health Sciences, Department of Biology, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland;2. Department of Molecular Neurobiology, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany;3. Department of Pharmacology, Gunma University Graduate School of Medicine, Maebashi, Japan;1. Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (Friedich-Alexander University Erlangen-Nürnberg), Erlangen, Germany;2. Translational Radiobiology, Department of Radiation Oncology, Universitätsklinikum Erlangen (University Hospital Erlangen), Erlangen, Germany;3. Department of Medicine 1, Kussmaul Campus for Medical Research & Translational Research Center, University of Erlangen-Nuremberg, Erlangen, Germany;4. Department of Dermatology, University Hospital Erlangen, Deutsches Zentrum Immuntherapie (German Center for Immune Therapy), Friedrich-Alexander-Universität Erlangen-Nürnberg (Friedich-Alexander University Erlangen-Nürnberg), Erlangen, Germany;5. Department of Dermatology, Georg-August-University Göttingen, Göttingen, Germany;6. Department of Dermatology and Allergy, University of Bonn, Bonn, Germany;1. Department of Dermatology, University of Michigan Medical School, Ann Arbor, Mich;2. Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Mich;3. Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Mich;4. Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi''an, Shannxi, China;5. Department of Dermatology, School of Medicine, UC-Davis Medical Center, Sacramento, Calif;6. Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Md;7. Department of Dermatology, Northwestern University, Chicago, Ill;8. Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich;9. Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany |
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| Abstract: | |
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| Keywords: | DEG"},{"#name":"keyword","$":{"id":"kwrd0015"},"$$":[{"#name":"text","_":"differentially expressed gene FC"},{"#name":"keyword","$":{"id":"kwrd0025"},"$$":[{"#name":"text","_":"fold change FDR"},{"#name":"keyword","$":{"id":"kwrd0035"},"$$":[{"#name":"text","_":"false discovery rate IFN"},{"#name":"keyword","$":{"id":"kwrd0045"},"$$":[{"#name":"text","_":"interferon KC"},{"#name":"keyword","$":{"id":"kwrd0055"},"$$":[{"#name":"text","_":"keratinocyte NN"},{"#name":"keyword","$":{"id":"kwrd0065"},"$$":[{"#name":"text","_":"healthy control sample PN"},{"#name":"keyword","$":{"id":"kwrd0075"},"$$":[{"#name":"text","_":"nonlesional sample PP"},{"#name":"keyword","$":{"id":"kwrd0085"},"$$":[{"#name":"text","_":"lesional sample RNA-seq"},{"#name":"keyword","$":{"id":"kwrd0095"},"$$":[{"#name":"text","_":"RNA sequencing |
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