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Association Between Regularly Occurring Complex Partial Seizures and Thyroid Function Parameters
Authors:Erik Taubø  ll,Kjell Torgeir Stokke,Leif Gjerstad,Yngve Lø  yning&dagger  ,Svein I. Johannessen&dagger  
Affiliation:Departments of Neurology, University of Oslo, Oslo;*Clinical Chemistry, Rikshospitalet, The National Hospital, University of Oslo, Oslo;†The National Center for Epilepsy, Sandvika, Norway
Abstract:
A 28-year-old man with regularly occurring clusters of complex partial seizures was studied over a total of 224 days. His seizure periods lasted 2-4 days and occurred at intervals of 5-6 weeks. Several parameters were studied. The most striking finding was an increase in the serum concentration of thyroxine prior to and during the seizure periods. The concentrations of urine catecholamines and serum cortisol also varied with the seizure periods, but these hormones increased after the seizure periods had begun. To determine if there is a general 4-6-week rhythm in thyroid hormone concentrations, 12 weekly blood samples from 10 healthy male students were analyzed. No rhythmicity was found.
Keywords:Complex partial seizures    Thyroid hormones    iological rhythms
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