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隐性脊柱裂流行病学及诊疗研究进展
引用本文:文建国,吴军卫,李一冬,邢玉荣,冯全得.隐性脊柱裂流行病学及诊疗研究进展[J].中华小儿外科杂志,2016(9):711-715.
作者姓名:文建国  吴军卫  李一冬  邢玉荣  冯全得
作者单位:1. 450052,郑州大学第一附属医院小儿尿动力中心、泌尿外科和河南省临床医学重点学科开放实验室;2. 450052,郑州大学第一附属医院体检中心
基金项目:国家自然科学基金面上项目(81373869),郑州大学优秀博士论文培育基金,河南省医学科技攻关计划项目(201503019)National Science Foundation of China(81373869),Scientific Research Foundation for Doctoral Program of Zhengzhou University,Medical Scientific Research Foundation of Henan Province(201503019)
摘    要:隐性脊柱裂(spina bifida occulta,SBO)是指有一个或数个椎骨的椎板闭合不全,脊柱背侧皮肤完整,椎管内的脊髓及神经组织不会直接突出于皮肤表面的脊柱裂.SBO可发生于脊柱任何部位,但常发生于腰骶部,可伴有脊髓神经发育畸形,产生神经系统、泌尿系统、消化系统以及运动系统等一系列临床症状和体征.SBO若伴有脊髓神经损伤会影响脊髓的正常解剖,使其受到异常牵拉,局部缺血、缺氧,可造成神经功能障碍而产生一系列临床症状,称脊髓栓系综合征(tethered spinal cord syndrome,TCS).国内外目前对SBO特别是合并TCS时的诊治存在一定争议,故本文就SBO的病因、发病率、及诊断治疗研究进展进行综述.

关 键 词:脊柱裂  隐性  流行病学  诊断

Recent advances in the prevalence,diagnosis and treatment of spina bifida occulta
Abstract:As a subtle form of dysraphism with one or more split spinous processes and widened interpedicular distances on plain radiography,spina bifida occulta (SBO) is often combined with intact dorsal skin.Occurring at the level of lumbosacral portion,it affects multiple systems,such as nervous,urological,digestive and motor systems.If associated with traction,hypoxic-ischemia and other malformations of spinal nerve lead to spinal nerve injury and manifest a series of related symptoms referred to as tethered spinal cord syndrome (TCS).In light of many controversies in its diagnosis and therapy,this review summarizes the pathogenesis,prevalence,diagnosis and treatment of SBO to assist its clinical management.
Keywords:Spina bifida occulta  Epidemiology  Diagnosis
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