| 四环素抑制胶原酶活性 |
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| 引用本文： | 王一 陈少军. 四环素抑制胶原酶活性[J]. 眼科研究, 1995, 13(1): 19-20 |
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| 作者姓名： | 王一 陈少军 |
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| 作者单位： | 第三军医大学西南医院眼科 |
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| 摘 要： | 对常用四种抗生素的抑活胶原酶作用进行了体外实验观察，结果表明，氯霉素，庆大霉素，青霉素对胶原酶活性无抑制作用，而四环素则显著抑制胶原酶活性，且抑活作用与浓度成正比。
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| 关 键 词： | 四环素 胶原酶 角膜溃疡 药物疗法 |
The Tetracycline Inhibits the Activity of Collagenase |
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| Wang Yi,et al. The Tetracycline Inhibits the Activity of Collagenase[J]. Chinese Ophthalmic Research, 1995, 13(1): 19-20 |
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| Authors: | Wang Yi et al |
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| Affiliation: | Wang Yi,et alDepartment of Ophthalmology,Southwestern Hospital,Third Military Medical College,Chongqing |
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| Abstract: | e have studied the role of four antibiotics which inhibit the activity of collagenase in vitro.The resultsshow that the penicilinum,the gentamycin and the chloromycetin do not inhibit the activity of collagenase,butthe tetracycline inhibits it markedly and the inhibited activity of collagenase has a parallel relationship withthe concentration of tetracycline. |
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| Keywords: | collagenase tetracycline penicilinum gentamycin chloromycetin |
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