氯吡格雷治疗不稳定性心绞痛疗效评价

目的　评价氯吡格雷在不稳定性心绞痛治疗中的作用。方法　选择 10 0例不稳定性心绞痛病例 ,分为氯吡格雷治疗组 (5 0例 )和对照组 (5 0例 ) ,观察住院期间、6个月及 1年后随访期间急性冠状动脉事件的发生率。结果　住院期间氯吡格雷治疗组发生冠脉事件 8例 ,占观察数 16 % ;对照组 18例 ,占 36 % ,P <0 .0 5。治疗后 6个月发生急性冠状动脉事件 2例 ,占 2 5 % ;对照组 6例 ,占 75 % ,P <0 .0 5。治疗后 1年发生急性冠脉事件 6例 ,占 33% ;对照组 12例 ,占 6 8% ,P <0 .0 5。结论　氯吡格雷治疗不稳定性心绞痛在住院期间 ,治疗后 6个月及 1年 ,均可减少急性冠脉事件的发生。

Clinical Effect Assessment of Unstable Angina Treated with Clopidogrel

Objective To assess the curative effect of clopidogrel treating unstable angina. Methods 100 cases of unstable angina patients were divided into test group and control group. The incidence rate of acute coronary heart disease was observed during hospitalization, 6 month and 1year later. Results During hospitalization, the incidence rate in testgroup was 16% and in control group was 36% (P<0.05). 6 months after treatment, the test group was 25% and in control group was 75% (P<0.05). 1 year after treatment the incidence rate in test group was 33% and in control group was 68% (P<0.05). Conclusion The clopidogrel could reduce the incidence rate of acute coronary heart disease.