HLA-A,-B,-C and-D Antigens in Male Patients with Myasthenia Gravis |
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| Authors: | J. Sä fwenberg,L. Hammarströ m,,J. B. Lindblom,G. Matell,,E. Mö ller,P. O. Osterman,C. I. E. Smith |
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| Affiliation: | Blood Center, University Hospital, Uppsala;Division of Immunobiology, Karolinska Institute, Wallenberglaboratory, Stockholm;Department of Medicine, South Hospital, Stockholm;Transplantation Immunology Laboratory, Huddinge Hospital, Huddinge;Department of Neurology, University Hospital, Uppsala, Sweden |
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| Abstract: | ![]()
HLA-A,-B,-C and-D antigens were determined in 54 male Myasthenia Gravis patients. A significant increase of the B8 antigen frequency was found among patients with an onset of the disease before the age of 35. No significant increase was found among the D antigens. In a combined male and female material with an early age at onset, thymic hyperplasia was correlated to the presence of HLA-B8. |
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