| HPLC法测定盐酸美沙酮含量 |
| |
| 引用本文： | 林彩,代青,董慧,马文秀,刘松青.HPLC法测定盐酸美沙酮含量[J].药学实践杂志,1997,15(5):299-301. |
| |
| 作者姓名： | 林彩 代青 董慧 马文秀 刘松青 |
| |
| 作者单位： | 第三军医大学西南医院!重庆，630038，第三军医大学西南医院!重庆，630038，第三军医大学西南医院!重庆，630038，第三军医大学西南医院!重庆，630038，第三军医大学西南医院!重庆，630038 |
| |
| 摘 要： | 本文采用高效液相色谱法，以盐酸布比卡因为内标，检测波长220nm，在Symmetry-C18柱上，以己腈-磷酸二氢钾（pH2．5）（3862，V／V）为流动相，测定盐酸美沙酮及其口服液的含量。方法平均回收率为100．17％，日内及日间的RSD均＜1％。方法简便、快速、准确。
|
| 关 键 词： | 盐酸美沙酮 盐酸美沙酮口服液 HPLC |
Determination of methadone hydrochloride by HPLC |
| |
| Lin Cai,Dai Qing,Dong Hui,Ma Wenxiu and Liu Songqing.Determination of methadone hydrochloride by HPLC[J].The Journal of Pharmaceutical Practice,1997,15(5):299-301. |
| |
| Authors: | Lin Cai Dai Qing Dong Hui Ma Wenxiu and Liu Songqing |
| |
| Institution: | Southwest Hospital, Third Military medical University Chongqing 630038;Southwest Hospital, Third Military medical University Chongqing 630038;Southwest Hospital, Third Military medical University Chongqing 630038;Southwest Hospital, Third Military medical University Chongqing 630038;Southwest Hospital, Third Military medical University Chongqing 630038 |
| |
| Abstract: | To estab1ish a HPLC method for determining methadone hydrochloride and methadone hydrochloride oral solution.Using a Symmetry-C18 Chlumn,a mixture of acetoni trile-monobasic potassium phosphate(pH2.5)(38:62,V/V)as mobile phase and detected at 220nm bupivacaine hydrochloride was used as internal standard.The average recovery was 100.17%.The RSD for the inter inter and intra-day were all less than 1%.The method is simple,rapid and accurate. |
| |
| Keywords: | methadone hydrochloride methadone hydrochloride oral solutinn HPLC |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《药学实践杂志》浏览原始摘要信息 |
| 点击此处可从《药学实践杂志》下载免费的PDF全文 |
