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Adhesion formation and interanimal variability in a laparoscopic mouse model varies with strains
Authors:Molinas Carlos Roger  Binda Maria Mercedes  Campo Rudi  Koninckx Philippe Robert
Affiliation:

aLaboratory of Experimental Gynecology, Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Belgium

bLeuven Institute for Fertility and Embryology, Leuven, Belgium

Abstract:
Adhesion formation after laparoscopic surgery was evaluated in mice of different strains. More adhesions were observed in Swiss, NMRI, and BALB/c mice, with less interanimal variability in BALB/c mice. These data point to genetics effects on adhesion formation, which open new insights in its pathogenesis and indicate the importance of a careful strain selection for animal studies.
Keywords:
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