先天性巨结肠患儿术后发生小肠结肠炎的危险因素及预防措施

目的探讨先天性巨结肠患儿术后发生小肠结肠炎的危险因素,并制定针对性预防措施。方法选择2017年1月—2019年1月在医院经根治性切除术治疗的先天性巨结肠患儿122例作为研究对象,对所有纳入对象完成追踪随访1年,根据患儿是否发生小肠结肠炎,分为病例组(发生小肠结肠炎)和对照组(未发生小肠结肠炎)。详细记录患儿的统计学资料,采用单因素及多因素Logistic回归分析影响先天性巨结肠患儿术后发生小肠结肠炎的危险因素。结果经多因素Logistic回归分析显示,营养不良、术前小肠结肠炎、肠道菌群紊乱及术后吻合口瘘或狭窄为影响先天性巨结肠患儿术后发生小肠结肠炎的危险因素。结论先天性巨结肠患儿术后小肠结肠炎发生率较高,且影响因素较多,应正确认识其影响因素的存在并积极干预,可有效减少或避免术后并发症给患儿术后康复带来的不利影响。

Risk factors and preventive measures of enterocolitis in children patients with congenital Hirschsprung's disease

Objective To explore the risk factors of enterocolitis in children patients with congenital Hirschsprung's disease after surgery and develop targeted preventive measures.Methods To select 122 cases of children patients with congenital Hirschsprung's disease treated by radical resection in hospital from January 2017 to January 2019 as the study objects.All included subjects were followed up for 1 year,according to whether the children patients had enterocolitis,they were divided into a case group(entercolitis)and a control group(no enterocolitis).The statistical data of the children patients were recorded in detail,and the single factor and multivariate Logistic regression analysis was used to analyze the risk factors of enterocolitis in children patients with congenital Hirschsprung's disease.Result Multivariate Logistic regression analysis showed that the malnutrition,preoperative enterocolitis,disturbance of intestinal flora,and postoperative anastomotic leakage or stenosis was all the risk factors affecting postoperative enterocolitis in children patients with congenital Hirschsprung's disease.Conclusion The incidence rate of postoperative enterocolitis in children patients with congenital Hirschsprung's disease was higher,and there were many influencing factors.The existence of its influencing factors should be correctly recognized and actively intervened,which can effectively reduce or avoid the adverse effects of postoperative complications on children's postoperative recovery.