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伴纵隔B3型胸腺瘤的肺上皮样血管内皮瘤临床病理观察
引用本文:樊翔,魏晓莹,王国庆,张丽华. 伴纵隔B3型胸腺瘤的肺上皮样血管内皮瘤临床病理观察[J]. 诊断病理学杂志, 2011, 18(2): 113-116. DOI: 10.3969/j.issn.1007-8096.2011.02.011
作者姓名:樊翔  魏晓莹  王国庆  张丽华
作者单位:东南大学附属中大医院病理科,南京,210009
摘    要:
目的提高对肺上皮样血管内皮瘤(PEHE)临床病理特征以及遗传学特点的认识。方法应用HE染色、免疫组化方法对伴纵隔B3型胸腺瘤的临床病理特征、免疫表型进行分析,并结合文献讨论。结果 PEHE好发于中年女性,临床无特异性症状,影像学检查表现为肺内多发或孤立性病灶;镜下显示黏液样或玻璃样变的背景中瘤细胞呈短索状或小巢状排列,可见胞质内空泡;肿瘤细胞表达血管内皮标记。结论肺上皮样血管内皮瘤少见,无特异性临床表现,诊断主要依靠组织病理学和免疫组化检查。

关 键 词:上皮样血管内皮瘤  胸腺瘤  肺肿瘤  病理学  免疫组化

Pulmonary epithelioid hemangioendothelioma associated with type B3 thymoma
FAN Xiang,WEI Xiao-ying,WANG Guo-qing,ZHANG Li-hua. Pulmonary epithelioid hemangioendothelioma associated with type B3 thymoma[J]. Chinese Journal of Diagnostic Pathology, 2011, 18(2): 113-116. DOI: 10.3969/j.issn.1007-8096.2011.02.011
Authors:FAN Xiang  WEI Xiao-ying  WANG Guo-qing  ZHANG Li-hua
Affiliation:FAN Xiang,WEI Xiao-ying,WANG Guo-qing,ZHANG Li-hua(Department of Pathology,Affiliated Zhongda Hospital,Southeast University,Nanjing 210009,China)
Abstract:
Purpose To observe and comprehend the pathological and genetic features of pulmonary epithelioid hemangioendothelioma(PEHE).Methods By using HE stain,immunohistochemistry,and revieweing the related literatures,the characteristics of the clinicopathology and immunophenotype were analysed in one case of pulmonary epithelioid hemangioendothelioma associated with type B3 thymoma.Results PEHE were predominant in the middle-aged women.They presented nonspecial clincal features.Almost all tumors showed multiple or...
Keywords:Epithelioid hemangioendothelioma  Thymoma  Pulmonary neoplasms  Histopathology  Immunohistochemistry  
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