Advances in the study of Alzheimer's disease |
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作者姓名: | Angue Nkoghe Francoise Yunman Li |
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作者单位: | Depatmmat of Pharmacology, Oaina Pharmaceutical University, Nanjing 210009, P.R. China. |
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摘 要: | Alzheimer' s disease (AD) is the most common cause of dementia, and the only treatment currently available for the disease is acetylcholinesterase inhibitors. Recent progress in understanding the molecular and cellular pathophysiology of Alzheimer's disease has suggested possible pharmacological interventions, including acetylcholineseterase inhibitors; secretase inhibitors; cholesterol lowering drugs; metal chelators and amyloid immunization. The objective of this paper is to review the main drugs possibly used for AD and their future therapeutic effects.
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关 键 词: | 老年性痴呆 病理机制 治疗方法 临床表现 |
收稿时间: | 2005-06-18 |
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