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| Ki-67在乳腺癌新辅助化疗中的作用及临床意义 | |
| 引用本文： | 滕冲,宋晓薇. Ki-67在乳腺癌新辅助化疗中的作用及临床意义[J]. 实用肿瘤学杂志, 2012, 26(2): 188-191 |
| 作者姓名： | 滕冲 宋晓薇 |
| 作者单位： | 哈尔滨医科大学附属第三医院内科,哈尔滨,150081 |
| 摘 要： | 新辅助化疗主要应用于局部晚期乳腺癌的治疗,疗效评价常用的指标为临床上缓解和病理学上缓解的程度.Ki-67是与细胞分裂增殖有关的核蛋白,已广泛应用于各种肿瘤的诊断及预后.多项临床研究资料表明Ki-67在判断乳腺癌新辅助化疗是否有效中显示出潜在的价值,现就Ki-67在乳腺癌新辅助化疗中的作用及临床意义作一综述. |
| 关 键 词： | Ki-67 乳腺癌 新辅助化疗 |
Effect and clinical significance of Ki-67 in neoadjuvant chemotherapy for breast cancer |
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| TENG Chong , SONG Xiaowei. Effect and clinical significance of Ki-67 in neoadjuvant chemotherapy for breast cancer[J]. Journal of Practical Oncology, 2012, 26(2): 188-191 | |
| Authors: | TENG Chong SONG Xiaowei |
| Affiliation: | TENG Chong,SONG Xiaowei(Department of Internal Medicine,The Third Affiliated Hospital of Harbin Medical University,Harbin 150081) |
| Abstract: | Neoadjuvant chemotherapy （NAC）is one of the main strategies for patients with locally ad- vanced breast cancer. Clinical and pathologic response rates are equivalent used for evaluating therapeutic effect. The expression of Ki - 67 protein is associated with cell proliferation. It has been widely used in the diagnosis and prognosis of various tumors. A number of clinical data indicate that Ki -67 demonstrated a potential value in de- termining the effectiveness of neoadjuvant chemotherapy for breast cancer. The role of Ki - 67 on neoadjurant chemotherapy and its clinical significance is reviewed. |
| Keywords: | Ki - 67 Breast cancer Neoadjuvant chemotherapy |
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