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4种抗原诊断血吸虫病效果的比较研究
引用本文:张顺科,易新元,曾宪芳,曾庆仁,李忠杰. 4种抗原诊断血吸虫病效果的比较研究[J]. 中国人兽共患病杂志, 2000, 16(5): 46-47
作者姓名:张顺科  易新元  曾宪芳  曾庆仁  李忠杰
作者单位:湖南医科大学寄生虫学教研室!长沙410078
摘    要:
目的 寻找特异性、敏感性较高,且价廉和制备简易的血吸虫病诊断抗原。方法 用酶链免疫吸附实验(ELISA)比较4种抗原检测58例慢性血吸虫病人的阳性率及41例正常人血清和104例其它寄生虫病人的阴性率。结果 SEA、SjMAg,rSj32和KLH4种抗原的敏感性分别为94.8%、98.3%,93.1%和96.6%,特异性分别为95.2%、97.9%、97.2%和99.3%。4种抗原之间敏感性和特异性

关 键 词:日本血吸虫 血吸虫病 抗原 血清学诊断

COMPARATIVE STUDY OF 4 ANTIGENS FOR THEIR POTENTIAS IN SERODIAGNOSIS OF SCHISTOSOMIASIS
ZHANG Shunke,YI Xinyuan,ZENG Xianfang,ZENG Qingren,LI Zhongjie. COMPARATIVE STUDY OF 4 ANTIGENS FOR THEIR POTENTIAS IN SERODIAGNOSIS OF SCHISTOSOMIASIS[J]. Chinese Journal of Zoonoses, 2000, 16(5): 46-47
Authors:ZHANG Shunke  YI Xinyuan  ZENG Xianfang  ZENG Qingren  LI Zhongjie
Abstract:
Aim To find schistosomiasis diagnosing antigens, that are cheaper, and higher sensitivity and specificity and easier in preparation. Methods 4 antigens, SEA, SjMAg, rSj32 and KLH were tested for the sensitivity in 58 chronic patients with shistosomiasis and the specificity in 41 normal persons and 104 patients with other parasitosis by ELISA. Results The respective sensitivity of 4 antigens was 94 8%, 98 3%, 93 1% and 96 6%, while the respective specificity of 4 antigens was 95 2%, 97 9%, 97 2%and 99 3%. There were no significant differences among the 4 antigens in terms of the sensitivity and the specificity. Conclusion SjMAg, KLH and rSj32 have the same value as SEA in diagnosing schistosomiasis japonica.
Keywords:Schistosoma japonicum   Schistosomiasis   Antigen   Serodiagnosis
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