中西医结合治疗激素敏感型系膜增生性肾炎疗效观察

目的评价中西医结合治疗激素敏感型系膜增生性肾炎的疗效。方法将122例呈肾病综合征表现并对强的松治疗敏感的非lgA系膜增生性肾炎患者随机分为两组，对照组按常规方法使用并撤减强的松，观察组在强的松常规治疗的基础上加用中药治疗。通过观察系膜增生性肾炎的复发及强的松副作用的发生情况评价中西医结合治疗系膜增生性肾炎的疗效。结果观察组系膜增生性肾炎的复发率及强的松副作用的发生率显著低于对照组（P＜0.01）。结论中西医结合治疗激素敏感型系膜增生性肾炎，可以明显减少复发率及强的松的副作用。

Observation on Effect of Integrated Chinese and Western Medicine in Treating Patients with Sensitive to Prednisone of Mesangial Proliferative Glomerulonephritis

Objective To evaluate the effect of integrated Chinese and Western medicine in treating patients with sensitive to prednisone of mesangial proliferative glomerulonephritis.Methods One hundred and twenty two patients of idiopathic nephrotic syndrome with no IgA mesangial proliferative glomerulonephritis and sensitive to prednisone treatment were divided into two groups randomly.The dosage of prednisone was used and reduced by routine in both groups but Chinese herbs treatment was added to the treated group.Results The recurrent rate of disease and occurrence rate of side-effects of prednisone in the treated group were less than in the control group significantly(P<0.01).Conclusion Integrated Chinese and Western medicine treatment of mesangial proliferative glomerulonephritis could extenuate markedly the recurrence rate of disease and the sideeffect of prednisone.