Department of Life Science, Tunghai University, Taichung, Taiwan, Republic of China. mhsieh@mail.thu.edu.tw
Abstract:
Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant spinocerebellar degeneration characterized by a wide range of clinical manifestations. In this review, we discuss the role(s) that heat shock protein 27 (HSP27) may play in the cell death process of spinocerebellar ataxia type 3.