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| 铜绿假单胞菌侵袭力的研究进展 | |
| 引用本文： | 张帆,黄梨莎,李玉. 铜绿假单胞菌侵袭力的研究进展[J]. 国际呼吸杂志, 2010, 30(20). DOI: 10.3760/cma.j.issn.1673-436X.2010.020.005 |
| 作者姓名： | 张帆 黄梨莎 李玉 |
| 作者单位： | 山东大学齐鲁医院呼吸内科,济南,250012;山东大学齐鲁医院呼吸内科,济南,250012;山东大学齐鲁医院呼吸内科,济南,250012 |
| 摘 要： | 铜绿假单胞菌极强的侵袭力是其能在院内感染致病菌中占主导地位的原因之一.侵袭力的测定方法主要是侵袭实验和单层细胞渗透法.侵袭力内容很广,包括黏附素(如菌毛、鞭毛、外膜蛋白等)和各种侵袭机制(如荚膜、侵袭性酶类、生物膜形成等).各个方面联系密切,其相关研究为抗菌治疗提供了新的思路. |
| 关 键 词： | 铜绿假单胞菌 侵袭力 黏附 生物膜 |
Research advence on invasiveness of Pseudomonas aeruginosa |
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| ZHANG Fan,HUANG Li-sha,LI Yu. Research advence on invasiveness of Pseudomonas aeruginosa[J]. International Journal of Respiration, 2010, 30(20). DOI: 10.3760/cma.j.issn.1673-436X.2010.020.005 | |
| Authors: | ZHANG Fan HUANG Li-sha LI Yu |
| Abstract: | The extremely strong invasiveness of Pseudomonas aeruginosa contributes to its leading role in nosocomial infection. Determination of invasiveness is mainly invasion assay and monolayer penetration assay. The contents on invasion are very wide,including adhesion (such as pili, flagella, outer membrane protein, etc. ) and various invasion mechanisms (such as capsules, invasive enzymes, biofilm formation,etc. ). They are closely related to each other and their researches provide new directions for antibacterial therapy. |
| Keywords: | Pseudomonas aeruginosa Invasiveness Adhesion Biofilm |
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