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Complications of combined radical hysterectomy and pelvic radiation
Authors:Jean Claude Remy M.D.   Rachel G. Fruchter Ph.D.   Kwang Choi M.D.   Marvin Rotman M.D.  John G. Boyce M.D.
Affiliation:1. Cabrini Monash University Department of Surgery, Cabrini Hospital, Malvern, VIC, Australia
;2. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, VIC, Australia;3. Department of Clinical Epidemiology, Cabrini Institute, Malvern, VIC, Australia;1. Department of General Surgery, Complexo Hospitalario de Ourense, Ourense, Spain;2. Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain;3. Department of General Surgery, Hospital de Verín, Ourense, Spain;4. Department of General Surgery, Hospital Santa Ana de Motril, Granada, Spain;5. CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain;6. Instituto de Investigación Biosanitaria IBS, Granada, Spain;1. Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan;2. Department of Materials Engineering, Ming Chi University of Technology, Taishan, New Taipei City 24301, Taiwan;3. Department of Nephrology, Chang Gung Memorial Hospital, Taoyuan, Taiwan;4. Department of Chemical and Materials Engineering, Chang Gung University, Guishan, Taoyuan 33302, Taiwan;5. Division of Nephrology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan;6. Department of Safety, Health and Environmental Engineering, Ming Chi University of Technology, Taishan, New Taipei City 24301, Taiwan;1. Service de chirurgie orthopédique et traumatologique, CHU La Milétrie, 2, rue de La Milétrie, 86000 Poitiers, France;2. Service de chirurgie orthopédique et traumatologique, centre hospitalier Georges-Renon, 40, avenue Charles-de-Gaulle, 7900 Niort, France
Abstract:
Long-term gastrointestinal (GI) and urinary tract (UT) complications were evaluated in 48 women treated by radical hysterectomy (RH) and pelvic node dissection (PND) and in 25 women who received 5000–5400 rad of external pelvic radiation (RT) after RH-PND. No major complications developed in the surgery-only group, but the 5-year minor GI complication rate was 4% and the 5-year minor UT complication rate was 10%. In 9 patients receiving RT at 200 rad/day, one major GI complication (13%) and one major UT complication (14%) developed. In 16 patients receiving RT at 180 rad/day only minor GI complications (7%) and minor UT complications (13%) developed. The conclusion is that after RH-PND, adjunctive RT delivered at 180 rad/day through four ports results in acceptable, minimal complications.
Keywords:
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