PET显像对卵巢癌诊断和监测治疗价值的初步探讨(附3例报告)

目的探讨PET显像诊断卵巢癌和监测治疗的价值.方法用siemensECAT47PET扫描仪对1例可疑卵巢癌患者及2例术后的患者行PET检查.3例患者均经病理证实为卵巢癌.PET检查前禁食6小时,空腹血糖控制在6.7mmol/l以下,并按5.55MBq/kg静脉注入18F-FDG,40分钟后检测.结果PET显示了术前1例B超阴性,肿瘤标志物CA125在正常范围内的透明细胞癌,经PET检查确诊并经病理证实.另2例术后化疗3周期的卵巢癌经PET检查,其中1例局部复发并全身转移,另1例仍无瘤生存.结论PET显像可用于卵巢癌的早期诊断,及术后化疗疗效监测且比B超及肿瘤标志物CA125等更具有敏感性.

The preliminary study on diagnosis and monitoring treatment of ovarian cancer by 18F-FDG-PET image

Objective To explore diagnostic and monitoring treatment value of ovarian tumors by 18F-FDG-PET image.Methods 3 cases of ovarian tumors were confirmed by pathology. 40 minutes after intravenous administration of 18F-FDG ,PET scan was performed on them by using Siemens ECAT47 scanner,and at the same time the blood glucose of examinees should be controlled to that less than 6.7mmol/l.Results PET image showed a case of clear ovarian cell cancer with normal CA125, which could not be found by B ultrasonography . PET image could not only display local recurrence of lesion in a postoperative case with serious ovarian adenocarcinoma, but also metastases in the lung and mediastina. The PET image of a postoperative patient with endometrioid carcinoma of ovary was normal.Conclusion PET image, which is much more sensitive than any other methods, such as B ultrasonography ,tumor marker CA125, could be used to make a diagnosis of stage I ovarian cancer and monitor postoperative chemotherapy effect.