老年人胃癌的临床特点及预后因素分析

目的分析老年人胃癌的临床特点以及影响预后的各种因素，更好的认识老年人胃癌的特征，为我们的诊断和治疗提供参考，从而改善他们的生存率。方法收集1994～1998年我院收治的老年人(≥65岁)胃癌356例．对预后进行单因素和Cox回归模型分析。结果老年人胃癌患者多为男性，症状以上腹疼痛、食欲减退和饱胀不适多见，病程长，确诊时多为晚期。多因素分析显示，年龄、分期、手术切除与预后有关。结论对于老年人胃癌早检查．早诊断是关键。尽可能实施D2式淋巴结清扫的胃癌根治术对提高五年生存率是十分必要的，对无根治手术条件的病人，姑息性切除手术也能改善预后。

ANALYSIS OF CLINICAL CHARACTERISTICS AND PROGNOSTIC FACTORS OF GASTRIC CANCER IN ELDERLY PATIENTS

Objective To better understand the clinical characteristics of gastric cancer in elderly patients and improve its diagnosis,management and prognosis. Methods 356 cases of eldly patients with gastric cancer admitted to Ruijin Hospital during 1994 to 1998 were studied by univariate analysis and Cox multivariate regression analysis. Results For elderly, the incidence of gastric cancer was still higher in male than female. Most of the cases were at late stage when diagnosed and usually with symptoms of epigastric pain,poor appetite and fullness for quite a long period. Conclusions The early detection and diagnosis are the key point for elderly gastric cancer patients. D2 radical gastrectomy is necessary to achieve better 5-year survival and palliative resection will also play some roles to improve the prognosis and quality of life when radical operation is not practical.