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| 卡马西平致红斑狼疮样综合征1例 | |
| 引用本文： | 姚勤,张峻,周琼. 卡马西平致红斑狼疮样综合征1例[J]. 药品评价, 2013, 0(24): 45-46 |
| 作者姓名： | 姚勤 张峻 周琼 |
| 作者单位： | 昆明医科大学第一附属医院临床药学科,云南昆明,650032 |
| 摘 要： | 1例42岁女性患者因癫痫服用卡马西平，2天后出现全身皮肤瘀点，口腔粘膜出血，5天后停用卡马西平，检查示血小板减少（PLT3＆#215;109/L），抗核抗体（ANA）和抗双链DNA抗体阳性。考虑红斑狼疮样综合征与卡马西平有关，给予糖皮质激素治疗，患者皮肤瘀斑逐渐消退，治疗3天后血小板计数恢复正常，2个月后抗核抗体和抗双链D N A抗体均为阴性，红斑狼疮样综合征未再出现。 |
| 关 键 词： | 卡马西平 红斑狼疮样综合征 药源性红斑狼疮 |
Carbamazepine-induced Lupus Erythematosus-like Syndrome |
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| YAO Qin,ZHANG jun,ZHOU Qiong. Carbamazepine-induced Lupus Erythematosus-like Syndrome[J]. Drug Evaluation, 2013, 0(24): 45-46 | |
| Authors: | YAO Qin ZHANG jun ZHOU Qiong |
| Affiliation: | YAO Qin, ZHANG jun, ZHOU Qiong |
| Abstract: | A 42-year-old femalepatient started receiving carbamazepine for epilepsy. After two days of treatment, the patient developed diffused ecchymosis all over the body. Carbamazepine was stoppedafter five days of treatment. Blood testing showed decrease in platelet count 3＆#215;109/L. Positive anti-nuclear antibodies and anti-dsDNAantibodies were detected in additional studies. Systemic lupus erythematosus was diagnosed and prednisone therapy was introduced. Two months after carbamazepine withdrawal, all symptoms had disappeared with the use of prednisone acetate. |
| Keywords: | Carbamazepine Lupus Erythematosus-like Syndrome Drug-induced Lupus Erythematosus |
| 本文献已被 CNKI 维普 等数据库收录！ | |