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The use of immunohistochemistry in liver tumors
Authors:Chan Elaine S  Yeh Matthew M
Affiliation:1. Institute of Pathology, Diakoniewerk Halle, Germany;2. Clinic of Urology, University Hospital Erlangen, Diakoniewerk Halle, Germany;3. Klinik für Allgemein und Visceralchirurgie, Diakoniewerk Halle, Germany;1. Center for Interventional Endoscopy, Florida Hospital, 601 East Rollins Street, Orlando, FL 32803, USA;2. Institute for Minimally Invasive Therapy, Florida Hospital, 601 East Rollins Street, Orlando, FL 32803, USA
Abstract:
A variety of benign and malignant neoplasms can be encountered in the liver. Hematoxylin and eosin-stained tissue sections alone may not yield sufficient information to definitively diagnose liver tumors; therefore, ancillary studies with immunohistochemical markers can play a crucial role in differentiating the different hepatic neoplasms. The recent development of oncofetoprotein glypican-3 has added to the value of immunohistochemistry in diagnosing liver cancer. This review discusses the immunohistochemical markers used most often in the diagnosis of hepatic tumors.
Keywords:
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