The use of immunohistochemistry in liver tumors |
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Authors: | Chan Elaine S Yeh Matthew M |
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Affiliation: | 1. Institute of Pathology, Diakoniewerk Halle, Germany;2. Clinic of Urology, University Hospital Erlangen, Diakoniewerk Halle, Germany;3. Klinik für Allgemein und Visceralchirurgie, Diakoniewerk Halle, Germany;1. Center for Interventional Endoscopy, Florida Hospital, 601 East Rollins Street, Orlando, FL 32803, USA;2. Institute for Minimally Invasive Therapy, Florida Hospital, 601 East Rollins Street, Orlando, FL 32803, USA |
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Abstract: | A variety of benign and malignant neoplasms can be encountered in the liver. Hematoxylin and eosin-stained tissue sections alone may not yield sufficient information to definitively diagnose liver tumors; therefore, ancillary studies with immunohistochemical markers can play a crucial role in differentiating the different hepatic neoplasms. The recent development of oncofetoprotein glypican-3 has added to the value of immunohistochemistry in diagnosing liver cancer. This review discusses the immunohistochemical markers used most often in the diagnosis of hepatic tumors. |
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