| 睡眠时间与动脉粥样硬化的关系研究进展 |
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| 引用本文： | 赵一贺,王虹剑. 睡眠时间与动脉粥样硬化的关系研究进展[J]. 中国分子心脏病学杂志, 2020, 0(2): 3349-3352 |
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| 作者姓名： | 赵一贺 王虹剑 |
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| 作者单位： | 中国医学科学院北京协和医学院国家心血管病中心阜外医院冠心病中心 |
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| 基金项目： | 中国心血管健康联盟《中国中青年临床研究基金-VG基金》(2017-CCA-VG-013)。 |
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| 摘 要： | 作为可调节的行为因素,睡眠与心血管事件的相关性正逐渐引起人们的关注。越来越多的研究显示,睡眠时间过长或过短,都会增加心血管事件的风险。其作用机制可能与内分泌、代谢因素、炎症反应以及血管内皮细胞功能损伤等机制相关。本文从流行病学、机制及干预措施等方面阐述睡眠时间对动脉粥样硬化发病率的影响及可能的病理生理学机制。
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| 关 键 词： | 睡眠时间 动脉粥样硬化 机制 |
Progress in the Relationship between Sleep Duration and Atherosclerosis |
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| ZHAO Yi-he,WANG Hong-jian. Progress in the Relationship between Sleep Duration and Atherosclerosis[J]. Molecular Cardiology of China, 2020, 0(2): 3349-3352 |
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| Authors: | ZHAO Yi-he WANG Hong-jian |
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| Affiliation: | (Coronary Unit,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100037,China) |
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| Abstract: | As an adjustable behavioral factor,sleep and its association with cardiovascular events have been gaining increased attention.A growing body of research has shown that both short and long sleep duration increase the risk of cardiovascular events.Potential mechanisms involve endocrinological,metabolic and inflammatory responses,as well as endothelial dysfunction.Through discussing epidemiology,mechanism and intervention measures,this review offers insight into the effect of sleep duration on atherosclerosis and the involved pathophysiological mechanisms. |
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| Keywords: | Sleep duration Atherosclerosis Mechanism |
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