Case-control association study of 36 single-nucleotide polymorphisms within 10 candidate genes for major depression and bipolar disorder |
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| Authors: | Concetta Crisafulli Alberto Chiesa Changsu Han Soo-Jung Lee Beatrice Balzarro Costanza Andrisano Antonina Sidoti Ashwin A. Patkar Chi-Un Pae Alessandro Serretti |
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| Affiliation: | 1. Department of Biomorphology and Biotechnologies, Division of Biology and Genetics, University of Messina, Messina, Italy;2. Institute of Psychiatry, University of Bologna, Bologna, Italy;3. Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy;4. Department of Psychiatry, College of Medicine, Korea University, Ansan, Kyeonggi-Do, Republic of Korea;5. Department of Psychiatry, Bucheon St. Mary’s Hospital, The Catholic University of Korea College of Medicine, Bucheon, Kyounggi-Do, Republic of Korea;6. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA |
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| Abstract: | ![]()
In this study we investigated 36 single nucleotide polymorphisms within 10 genes previously associated with major depression and bipolar disorder, as well as with the response to their treatment (ABCB1, ABCB4, TAP2, CLOCK, CPLX1, CPLX2, SYN2, NRG1, 5HTR1A and GPRIN2). No association with mood disorders and clinical outcomes was observed. |
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| Keywords: | Major depression Bipolar disorder Single nucleotide polymorphisms |
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