| 体质指数与总死亡率关系的Meta分析 |
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| 引用本文： | 李静静,陈裕明. 体质指数与总死亡率关系的Meta分析[J]. 疾病控制杂志, 2011, 15(11): 943-948 |
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| 作者姓名： | 李静静 陈裕明 |
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| 作者单位： | 1. 中山大学公共卫生学院流行病与卫生统计学系,广东广州 510080;广东省妇幼保健院,广东广州 510010
2. 中山大学公共卫生学院流行病与卫生统计学系,广东广州,510080 |
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| 基金项目： | 中山大学临床研究5010计划(2007032) |
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| 摘 要： | 目的采用Meta分析方法定量综合国内外前瞻性研究中不同水平体质指数(body mass index,BMI)与总死亡率关系。方法以体质指数、超重、肥胖、死亡率、队列研究、前瞻性研究及随访研究为主题词和关键词联合检索PubMed和中国期刊网全文数据库(CNKI),查找相关文献。合格的文献限定于探讨普通人群BMI与总死亡率关系的前瞻性研究,BMI分组数≥6,且报道了各组死亡的相对危险度(RR)及95%可信区间(95%CI)。结果共纳入32篇文献,含54个队列研究(总人数:7 910 932人,死亡数:1 376 997人)。男女合并发现,BMI和总死亡风险呈U形关系,总死亡风险最低时的BMI为23.0~24.9 kg/m2。与此对照,其他BMI组总死亡风险RR(95%CI)分别为:<18.5 kg/m2:1.53(1.49~1.57);18.5~20.9 kg/m2:1.09(1.07~1.11);21.0~22.9 kg/m2:1.06(1.04~1.08);25.0~26.9 kg/m2:1.01(1.00~1.03);27.0~29.9 kg/m2:1.11(1.10~1.12);30.0~34.9 kg/...
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| 关 键 词： | 死亡率 前瞻性研究 Meta分析 |
Meta-analysis for the relationship between body mass index and all-cause mortality |
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| LI Jing-jing,CHEN Yu-ming. Meta-analysis for the relationship between body mass index and all-cause mortality[J]. Chinese Journal of Disease Control and Prevention, 2011, 15(11): 943-948 |
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| Authors: | LI Jing-jing CHEN Yu-ming |
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| Affiliation: | LI Jing-jing1,2,CHEN Yu-ming1.1.Department of Epidemiology and Biostatistics,School of Public Health,Sun Yat-sen University,Guangzhou 510080,China,2.Guangdong Women and Children Hospital,Guangzhou 510010 |
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| Abstract: | Objective This meta-analysis aims to pool the overall effect of varied levels of body mass index(BMI) and total mortality generated from prospective studies.Methods We searched the PubMed and CNKI using the keywords of BMI,overweight/obesity,mortality,deaths,prospective/cohort/follow-up.Eligible studies reported relative risks(RR) of total mortality by at least 6 BMI levels in general populations were included.Results We included 32 papers,consisting of 54 independent cohorts(1 376 997 deaths from 7 910 932... |
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| Keywords: | Mortality Prospective studies Meta-analysis |
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