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2010-2014年上海地区医院抗高血压药物利用趋势
引用本文:席宇飞,吴英理,归成,寿佳慧,朱冠华. 2010-2014年上海地区医院抗高血压药物利用趋势[J]. 川北医学院学报, 2017, 32(1): 120-124. DOI: 10.3969/j.issn.1005-3697.2017.01.034
作者姓名:席宇飞  吴英理  归成  寿佳慧  朱冠华
作者单位:上海交通大学医学院,上海,200025;上海交通大学医学院病理生理教研室,上海,200025;上海交通大学附属第一人民医院临床药学科,上海,200080
摘    要:
目的:调查上海地区医院高血压治疗药物使用情况,评价其用药合理性,为药监管理部门、医疗保险机构以及药物生产经营企业提供决策依据,促进医疗机构用药水平,维护人民群众身体健康。方法:统计2010-2014年上海市地区119家样本医院采购的高血压治疗药物的分类、规格、用量等,运用药物利用研究中的限定日剂量、用药频度等方法对数据进行分析和评价。结果:钙通道阻滞剂(CCB)和血管紧张素受体阻断剂(ARB)等药物用药频度处于领先地位。新型固定复方制剂和β受体阻滞剂类的抗高血压药物用量增长迅速,传统固定复方制剂的用药频度下降明显。结论:上海地区抗高血压药物的应用基本符合治疗指南,抗高血压药物应用需求呈增长趋势,市场前景良好。

关 键 词:抗高血压药物  药物利用研究  限定日剂量

Utilization trend of antihypertensive drugs in hospitals in Shanghai district from 2010 to 2014
XI Yu-fei,WU Ying-li,GUI Cheng,SHOU Jia-hui,ZHU Guan-hua. Utilization trend of antihypertensive drugs in hospitals in Shanghai district from 2010 to 2014[J]. Journal of North Sichuan Medical College, 2017, 32(1): 120-124. DOI: 10.3969/j.issn.1005-3697.2017.01.034
Authors:XI Yu-fei  WU Ying-li  GUI Cheng  SHOU Jia-hui  ZHU Guan-hua
Abstract:
Objective:To investigate the utilization condition of antihypertensive drugs in the hospitals in Shanghai,and to evaluate the reasonability of drug administration,so as to provide basis for the decision of food and drug administration,medical insurance institution and drug manufactures and operating enterprises,promote the level of drug administration in medical institution,and preserve the body health of public population.Methods:Statistical analysis of the classification,specification and dosage of antihypertensive drugs purchased from 119 sample hospitals in Shanghai from 2010 to 2014 were made,so as to analyze and evaluate the data of defined daily dosage and frequency of drug administration.Results:The frequency of calcium channel blockers(CCB) and angiotensin receptor blockers (ARB) in a leading position.The dosage of new fixed compound agents and β receptor antagonists increased quickly while that of traditional fixed compound agents decreased prominently.Conclusion:The application of antihypertensive drugs in Shanghai basically confirms to the therapeutic guidelines,and their application demand is showing an increasing tendency,with excellent market prospect.
Keywords:Antihypertensive drug  Drug utilization study  Defined daily dose
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